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SECOND CALL FOR PAPERS
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Spurred by the advancement in synthetic biology (Gibson et al., 2010) at the J. Craig Venter Research
Institute the editors of Cognitive Computation Journal (Springer Science) invite submissions to a
special issue on biological substrates as a computational diaphragm.

This topic leads to further research questions on computation and the bio-signals produced by living
organisms. We anticipate submissions will contribute to the identification of a new breed of technologies:
1.) bio- computing applications (synthetic biology); 2.) chemical/microbial induced biological 
configurations; 3.) enhancing cognition and animal models; and 4.) neuroengineering sensory circuits
and clinical/biomedical research. This special issue will provide a forum for interdisciplinary 
discussion that points towards the next step in cognition and computing through the excitability of
biological substrates. 

The integration of computation and cognition on biological grounds has the prospect of pointing at 
a boundary system that is excitable, configurable, and manipulated within the framework of living 
organisms and their biological substrates. The next step in the development of natural computing 
hinges upon the development of biological substrates as a computational diaphragm. 

Authors are invited to submit unpublished research, original position papers, or literature reviews
that address challenges unique to bio-inspired computation. Relevant areas of investigation and 
expertise include, but are not limited to: 

• synthetic biology, systematic biology, soft-computing • computation theory (membrane, natural, quantum, or evolutionary) • bio-nanotechnology, computational biology, computational linguistics • medical informatics (decision making, medical diagnostics, catastrophic disease research) • underlying spatial and self-modulating aspects of biological substrates (sRNA, siRNA, proteomics) • bio-optics: quorum sensing, bio-markers, molecular probes • neurobiology, gene regulation, neural circuits • pharmaceutical and biomedical cellular delivery systems • chemical ecology, interfacing with aliphatic odors (GPCR encoding) • neural signal transduction, neurotransmitters • neuroimaging, neuroanatomy, neurophysiology • mirror neurons, neuropsychology, theory of mind, simulation theory • swarm intelligence, theory of intelligence, consciousness • hierarchical temporal memory, heterogenous logic • neuroplasticity, learning, memory • “games with purpose” or collaborative task experimentation • bayesian biomedical techniques (clinical studies, morphological data, in vitro embryo selection) • translational cognition for decision support in critical care environments • soft-computing research and control of unknown diseases • “molecule to man” decision support in individualized e-health • biomedical informatics and pharmacogenomics • animal behavior, transgenics models • developmental biology, embryology • linguistic or philosophic barriers to bio-computing • cladistics, detecting and overcoming systematic errors in genome-scale phylogenies 

This special issue places into perspective computation and cognition from a post-genome viewpoint. 
Since the Human Genome Project recent discovieries suggest a bio-computation that specifies a more
complex mechanisms along a multi-scale. Where a micro-meso-macro feedback occurs as a systemic 
self-organization with non-linear dynamics. Participation in this project proposes to advance the 
break with the "dogma" of one gene producing only one class of protein, assumed in the classic 
Monod-Changeux-Jacob model of the "Operon.the phenotype of living systems the incubation of 
bio-computing may gain strides through experimental literature on "small RNAs" (sRNA) interfering
with gene expression and protein production. Through the manipulation of biological substrates 
emerges the prospect to identify recipes for combinatorial, multidimensional, and topological 
organizations with a dynamics that escape conventional spatial or temporal-spatial representation.
A biological substrate represents a self-contained symbolic and logical neighborhood. 

This special issue is expected to appear in JUN 2012. 

Post submissions at: http://www.editorialmanager.com/cogn/
Co-Editors Alfredo Pereira Jr., Eduardo Massad, Nathaniel Bobbitt bobbittn@cwu.edu Important Dates
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Submission of full paper (to be received by): MAY 16, 2011 First notification of acceptance: AUG. 15, 2011 Submission of revised papers: OCT 15, 2011 Final notification to the authors: JAN 15, 2011 Submission of final/camera-ready papers: FEB 15, 2012 

http://www.springer.com/biomed/neuroscience/journal/12559?detailsPage=press